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It has been recently shown [60] that T cells from depressed patients displayed a compromised metabolic profile accompanied by heightened gene expression of CTP1a (carnitine palmitoyltransferase 1 A), the mitochondrial enzyme responsible for ACs synthesis
~7% for tirzepatide in SURMOUNT-1) and a new dysesthesia signal at ~21% incidence that didn't appear in Phase 2
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