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42 A long-term prospective cohort study involving 2088 participants found that higher serum TMAO levels were associated with an increased risk of T2DM and elevated fasting blood glucose
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NAPQI rapidly reduces GSH level, overwhelms the livers antioxidant defenses and binds to cellular macromolecules, triggering oxidative stress, mitochondrial dysfunction, and cell death pathways including ferroptosis (Jaeschke et al
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