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A dose-escalation approach was used, meaning participants started at a lower dose that was gradually increased over several weeks to reach the target dose
and a medication history was defined as having regularly taken relevant medications in the last 12 months
Molecular studies use GHSR-1a-transfected cell lines to measure receptor binding affinity (Ki), functional cAMP accumulation, and beta-arrestin recruitment in order to understand ipamorelin's signaling bias relative to native ghrelin
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A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice
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