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KPV is the C-terminal fragment of alpha-melanocortin (-MSH), a peptide hormone naturally produced by the body

These characteristics position UroA as a promising candidate for dietary supplementation, particularly for individuals aiming to enhance mitochondrial function and mitigate the effects of ageing

Its activity intersects two major metabolic pathways simultaneously: the NAD+ biosynthesis pathway (by consuming nicotinamide, an NAD+ precursor, NNMT competes with the NAD+ salvage pathway) and the methyl-donor pathway (by consuming SAM, NNMT reduces the availability of methyl groups for epigenetic and metabolic methylation reactions)

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