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Combined activation of GLP-1, GIP, and GCG systems theoretically provides complementary mechanisms: GLP-1-mediated insulin sensitization and satiety promotion, GIP-mediated enhancement of insulin secretion and adipose lipid buffering, and glucagon-mediated direct hepatic lipid oxidation and energy expenditure augmentation
Most people begin to see significant weight loss within 4-8 weeks of starting treatment, with optimal results typically achieved after 6-12 months
Clinical studies have shown that GLP-1 medications can effectively promote weight loss in patients who do not have diabetes
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