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The agency determined there is no clinical need to allow large compounding facilities to make large quantities of medicines from semaglutide, the ingredient in Novo Nordisks Wegovy weight loss and Ozempic diabetes treatments, as well as tirzepatide, the ingredient in Eli Lillys Mounjaro diabetes drug and Zepbound obesity medicine

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While these gastrointestinal symptoms are generally mild to moderate and tend to diminish over time as the body adjusts to treatment, they can occasionally be severe enough to warrant dose adjustment or discontinuation