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These factors do not equate to visible muscle gain

(2022) aerobic exercise produces moderate to large improvements in overall cognitive function in healthy elderly individuals and patients with mild cognitive impairment (MCI), but is ineffective in dementia patients

In vascular dementia (VD), chronic cerebral ischemia drives ferroptosis through dual mechanismsiron metabolism imbalance (upregulation of transferrin and its receptor TfR1 and downregulation of iron export protein FPN) results in the buildup of free iron within neurons, while oxidative stress accelerates lipid peroxidation by inhibiting GPX4 synthesis and upregulating ACSL4

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