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The Lewy body is thought to be an aggregating response in cells (Mikiei et al., 2004), which suggests that their function may be related to protein folding and aggregation defects (Mikiei et al., 2004

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Preclinical studies in murine and human alveolar macrophages (AMs) have demonstrated that loperamide induced autophagy, enhancing its antimicrobial activity towards M.tb [12]