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Furthermore, mitochondrial dysfunction promotes NLRP3 inflammasome assembly and caspase-1 activation, leading to the secretion of pro-inflammatory cytokines like IL-1, which are associated with the aberrant activation of CDK5 [53, 54]
However, long-term co-cultures with neural stem cells have proven difficult due to the relative immaturity of astrocytes (Krencik et al., 2011)
the trypanothione or the NADPH cavity) were tested in the inhibition assay
European Journal of Endocrinology , 151(Suppl 1), S17S24
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