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Discussion Our concept, which we verified in several previous paper [24, 32, 33, 42], is that if we mimic the specific expression pattern of nutrient transporters at the BBB with a combination of two or three different ligands a more specific targeting of nanoparticles across the BBB can be achieved

Taken together, current literature supports further investigation but underscores the need for well-controlled human clinical trials to determine safety, dosing, and efficacy

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BPC-157 is typically framed as the more targeted, tissue-specific option in recovery research, while TB-500 is more often positioned as the broader systemic option tied to cell migration, tissue remodeling, and recovery support