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Similar to the amphetamines, phentermine increases the release of norepinephrine and dopamine from nerve terminals and inhibits their reuptake
However, local populations may be threatened by habitat destruction, particularly the draining of wetlands for agriculture and human settlement
These results surpass any single approved GLP-1 drug
Yet, de novo choline synthesis in humans is not sufficient to meet their metabolic needs such that healthy humans fed choline-deficient diets develop fatty liver, liver damage, and/or muscle damage (see Deficiency)
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