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Harris uses a start low, go slow dosing approach to help minimize discomfort and support a smooth experience
While this decrease in DHT was not significant after 6 months, it may still have clinical significance or practical importance
As we learn more about these medications, its becoming clear that they can be helpful for people with other health conditions
How injectable/oral GLP-1 medications work: Mimic the GLP-1 hormone with engineered modifications for extended duration Bind to GLP-1 receptors to enhance insulin release and reduce glucagon Slow gastric emptying by 20-50%, promoting satiety Supported by large randomized controlled trialsthe STEP trials showed 14.9% mean weight loss at 68 weeks versus 2.4% for placebo The short answer on why patches cant deliver these drugs: GLP-1 molecules are relatively large peptide chains (molecular weight 3-5 kDa) that cannot effectively penetrate the skin barrier through passive transdermal diffusion
