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A potential strategy for achieving complete and relapse-free tumor remission involves combining conventional chemotherapy to target the bulk of tumor cells with drugs that inhibit glutathione synthesis to eliminate TICs
Reduced glutathione functions by donating electrons to free radicals, neutralizing them and preventing cellular damage
Tirzepatide, a dual GIP/GLP-1 receptor agonist, showed even greater weight loss in non-diabetic patientsup to 22% body weight reduction in some trial armsbecause it engages additional appetite-control pathways
As a tripeptide, glutathione is subject to destruction in the small intestine [35]
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![PDF] Tirzepatide-Induced Injection Site Reaction](https://figures.semanticscholar.org/18fb0b8dbc04c04a7b5177d9fd87256fc7c060bb/2-Figure1-1.png)
