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For example, in alveolar macrophages, GLP-1 receptor agonism suppressed activation of the NLRP3 inflammasome and reduced production of IL-1 [65], an effect in part mediated by the disruption of histone lactylation, a recognised regulator of pro-fibrotic gene expression [65]
Reiter RJ, Tan DX, Korkmaz A, Fuentes-Broto L
Results of a controlled clinical trial of glutathione in cases of hepatic cirrhosis
Semaglutide activates pathways that promote cell proliferation, particularly in tumors with high levels of GLP-1 receptors
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