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Some patients choose to combine B12 / MIC injections with NAD+ therapy, nutrition optimization, exercise, and other medically supervised wellness programs for more comprehensive support

Assessment at the four-week mark helps determine whether dose adjustment is needed

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if neurological involvement is present, maintenance is every two months Oral therapy is generally not appropriate where absorption is impaired (e.g., pernicious anaemia), as adequate levels cannot be reliably achieved Because B12 is water-soluble and any excess beyond hepatic storage capacity is excreted in the urine, it has a low toxicity profile