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It impairs physical function and independence, particularly concerning for older adults
Fuel Your Active Lifestyle: L-Carnitine is a naturally occurring amino acid derivative that amplifies the body's capacity to transport long-chain fatty acids to mitochondria, where they metabolize to generate energy
Additionally, in wild-type mice that overexpressed hHPN WT , there was a significant reduction in Cx32 expression, i.e., approximately 50 9% compared with both the AAV-hHPN RS and the vector-control (AAV-EGFP) groups (Fig
Finally, prospects for ferroptosis-based interventions and future directions point to several promising treatment avenues, including regulating iron homeostasis via chelators or TfR1/FPN modulation, using antioxidants and lipid peroxidation inhibitors to target GPX4 and ACSL4, or employing gene therapies and stem cell/exosome approaches to combat ferroptosis
