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This process, called slow titration, is one of the best ways to prevent or lessen gastrointestinal side effects
For example, if you are taking blood pressure or cholesterol-lowering medication, the same dose may become too strong after substantial weight loss
Similarly, in another meta-analysis including 47 RCT and more than 23 thousand patients, patients receiving different GLP1RAs had a mean difference in weight of -5 kg relative to placebo [10]