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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
A general rule of thumb is that higher doses of Topamax may lead to greater weight loss, but this comes with an increased risk of side effects
For comparisons of categorical variables, 2 tests were applied
According to the Saxenda SmPC and NICE Technology Appraisal 664, treatment should be discontinued if at least 5% of initial body weight has not been lost after 12 weeks on the full 3.0 mg daily dose (a lower threshold applies for people with type 2 diabetes)
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