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Effects of tirzepatide on cardiac injury and kidney function Treatment with tirzepatide resulted in a significant reduction in myocardial injury reflected by high-sensitivity troponin T as compared with placebo at both 24 and 52 weeks (ETD 24 weeks 9.8% (95% CI 16.0 to 3.3), P = 0.004, 52 weeks 10.4% (95% CI 16.7 to 3.6), P = 0.003), with no significant effect at 12 weeks (Fig

But cost should be weighed alongside the other factors below, not treated as the only variable

The trial is open-label, meaning both investigators and participants know which treatment they are receiving

According to Apovian, the drugs can be made in different countries without the same safety and manufacturing requirements that are required for FDA-approved drugs