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Tesamorelin can cause water retention, joint discomfort, and glucose changes due to its stronger GH stimulation, requiring more careful monitoring in research protocols
Headache with fever, stiff neck, confusion, or rash
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Organ and tissue growth concerns Because IGF-1 signaling affects cellular growth and proliferation throughout the body and not exclusively in skeletal muscle, there is concern that long-term use of IGF-1 could result in increased growth of other tissues/organs in the body
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