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However, a systematic approach to assessment and management is appropriate when heart rate changes are detected or when patients report cardiovascular symptoms
References DAscanio AM, Mullally JA, Frishman WH
This means running them together should not dramatically increase the burden of side effects compared to running either one alone
They use the first few weeks from a vial reconstituted at lower concentration (5 mL water for 2 mg/mL) for the early phases when precision matters most
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