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Centrally, GLP-1 promotes satiety through the activation of GLP-1 receptors in the hypothalamus and brainstem, which causes a reduction in food intake
In the 15 mg group, 63% of participants achieved a weight loss of over 20% of their body weight
In the randomized controlled trial carried out by Glauser and colleagues, it was found that initial monotherapy with VPA for children with newly diagnosed childhood absence epilepsy exerted superior efficacy for seizure control without unsatisfactory adverse events compared to other AED such as lamotrigine [156]
This unique feature lowers waste and reduces the cost of treatment
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