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Rapid weight loss increases cholesterol secretion into bile, promoting gallstone formation and triggering complications such as cholecystitis or biliary colic
The placebo- adjusted remission rates at week eight match or exceed most recent inflammatory bowel disease (IBD) entrants, such as Skyrizi, Tremfya and Velsipity, trailing only Rinvoq which remains second-line due to JAK class concerns
However, your metabolism will be even higher if you have a significant amount of muscle mass
Semaglutide and tirzepatide slow gastric emptying, which increases the risk of aspiration during anesthesia
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