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Qsymias cognitive effects do not respond well to any intervention other than stopping the topiramate component

In such cases, the appetite-suppressing effects of GLP-1RAs could potentially exacerbate behaviors like dietary restriction and dietary restraint, two behavioral patterns that help sustain eating disorder psychopathology, thus complicating treatment for these disorders

6a and Extended Data Fig

38 Additionally, ALC modulates neurotransmitters by increasing serotonin levels and enhancing dopamine and serotonin output in meso-cortico-limbic areas, potentially protecting against stress