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These therapeutic options can be used for weight control in patients with immune-mediated dermatosis who meet the above criteria
Figure 5 The SURMOUNT-1 study was a clinical trial of 72 weeks performed in 2539 obese patients without T2D that were randomized in four arms with placebo or TZP at the dose of 5mg,10 mg or 15 mg (72)
Some patients have found benefit in combining their GLP-1 therapy with supportive peptides
list prices (2025): $900$1,300 per month without insurance $11,000$16,000 per year at retail pricing Manufacturer coupons typically expire after 612 months Coverage reality: Medicare: limited obesity coverage Medicaid: varies by state Employer plans: increasingly restrictive prior authorization Weight regain often occurs after discontinuation Projected pricing trends: Near-term (35 years): modest price erosion, not collapse Medium-term (510 years): biosimilars and next-gen entrants may reduce prices 3050% Long-term: combination therapies likely raise per-patient spend again This is not a short-course drug market
