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This could be explained by the leanness of the Japanese population at the baseline, by the anabolic effect of improved cell function, or even because of the low dose employed in this trial [44]
Other GLP-1 drugs have similar effects, with muscle accounting for 25% to 39% of the total weight lost
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The 2013 Endocrinology paper used a GHRH-receptor-targeted botulinum-neurotoxin construct to characterise pulsatile GH secretion mechanisms (PMID 23825127)
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