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Mitochondrial GPx1 decreases induced but not basal oxidative damage to mtDNA in T47D cells

10.1016/j.biochi.2011.09.008 6 AlvarezM

A landmark six-month randomized controlled trial published in the European Journal of Nutrition by Richie et al

RSL3 inhibits mTOR signaling in thyroid cancer cells The mTOR signaling pathway has recently been implicated in counteracting ferroptosis by regulating ROS production 20 , therefore, it was important to examine the effects of RSL3 on mTOR signaling pathway and its downstream proteins and whether inactivation of mTOR pathway signaling will occur in thyroid cancer cells with GPX4 inhibition