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Recent results demonstrating agonism at the arcuate nucleus (ARC) revealed that signaling via Y1-Rs protected female mice from obesity (Paterlini, Panelli et al
For one-way ANOVA with seven groups, assuming a medium-to-large effect size ( f = 0.40), error probability of 0.05, and desired statistical power (1-) of 0.80, the calculated minimum sample size was 5 animals per group
Glutathione serum therapy can be administered weekly or every 15 days
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