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Recently, a large phase 3 placebo-controlled trial involving 3,649 women with high-risk operable breast cancer found no difference in invasive disease-free survival or cancer mortality between those who received adjuvant metformin and those who received standard therapy [37]

For patients who have significant needle anxiety or strongly prefer oral medications, this availability difference can be the deciding factor between the two classes

Some telehealth companies still offer compounded GLP-1s by using alternative language like GLP-1/GIP protocols or customized formulations. However, these are not FDA-approved and selling them without a documented clinical justification may be considered illegal

AOD-9604 Commonly used to support fat metabolism, stubborn fat reduction and body composition optimization, especially abdominal fat