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The critical role of NRF2 was confirmed, as these effects were partially reversed by NRF2 inhibitors
Vagal afferent neurons (VANs) expressing GLP-1Rs innervate intestinal mucosa and hepatic portal vasculature, suggesting these pathways may transduce peripheral GLP-1 RA effects to central satiety and glucoregulatory centers 57,58,59
GLP-1 is a hormone that our bodies naturally produce
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