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Headaches: Some users report headaches, particularly when starting the peptide or increasing doses

The STEP 4 trial showed that discontinuing semaglutide results in regaining approximately two-thirds of lost weight within a year

Microvascular decompression surgery is most effective for classical trigeminal neuralgia with a matching vascular compression pattern

In clinical trials of semaglutide injection for weight management, acute pancreatitis was confirmed by adjudication in 4 semaglutide-treated patients (0.2 cases per 100 patient-years) versus 1 in placebo-treated patients (less than 0.1 cases per 100 patient-years)