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Patients with pernicious anaemia, malabsorption disorders (such as Crohn's disease or coeliac disease), or following gastric surgery require regular B12 supplementation to prevent serious complications including megaloblastic anaemia and neurological damage

Factors That Affect How Long B12 Injections Last Several factors may influence how long the effects of a B12 injection last in your system, potentially explaining why some patients require more frequent injections than others, even with the same underlying condition

PMID 35987379

Evaluated in controlled preclinical settings for synergistic extracellular matrix dynamics