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Efpeglenatide and clinical outcomes with and without concomitant sodium-glucose cotransporter-2 inhibition use in type 2 diabetes: exploratory analysis of the AMPLITUDE-O trial

The reconstitution technique remains identical

When demand for GLP-1s and GIP/GLP-1s leaped past what the manufacturers could provide, compounded versions popped up in online pharmacies and brick-and-mortar stores, for the following drugs: Ozempic (semaglutide) Rybelsus (semaglutide) Wegovy (semaglutide) Zepbound (tirzepatide) Mounjaro (tirzepatide) Retatrutide (This drug is not FDA approved.) However, the FDA cautions that compounded drugs, while useful or even necessary in some situations, are not FDA-reviewed or approved, so the FDA cannot guarantee their safety, quality, or effectiveness

And we have studies that GLP ones can help improve cardiovascular outcomes in the right population