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It is notable that high spikes of blood insulin, (Hyperinsulinemia), initiates inflammation, which over times causes atherosclerosis and its sequela cardiovascular heart disease (CHD).ii High insulin is very, very bad

In the 1990s, researchers discovered that Gila monster saliva contains a peptide called exendin-4, which acts like GLP-1 but resists enzymatic breakdown

Even before the advent of GLP-1s, weve always known that weight loss is associated with some amount of muscle loss, says Dr

Non-incretin-based pharmacological options include naltrexone-bupropion (Contrave), which acts on central nervous system pathways regulating appetite and reward