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Ascorbic acid, commonly known as vitamin C, is a water-soluble vitamin
Most of the time it is used while manufacturing creams or skin-brightening tablets for consumption
This process, along with GCL inhibition and the formation of mixed disulfides between GSH and protein sulfhydryl, concurred to a steady-state decrement of free GSH concentration and, consequently, to an intracellular redox state shift toward more oxidizing conditions, which could be required for avoiding fast reduction of oxidized cysteines allowing the upstream ROS-induced autophagic stimulus to be propagated
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