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Remember: 850mg/L: greatest risk for serious or life-threatening effects including coma, respiratory depression, metabolic acidosis, hypotension Ammonia levels: may be helpful in predicting presence of underlying encephalopathy and/or development of cerebral oedema in patients who are mechanically ventilated and sedated (Clay and Hainline, 2007) The ICU resident now wants to know: Are we going to dialyse this patient
The strongest evidence comes from a 6-week RCT demonstrating superior efficacy of liraglutide in reducing BAD symptoms as compared with colesevelam currently considered standard-of-care treatment
Its best to avoid taking Dihexa close to bedtime
In the Phase 2 trial, 42% of participants on the 12 mg dose reported nausea, mostly in the first 4 to 8 weeks during dose escalation
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