surmount-1 tirzepatide trial weight loss non-diabetic after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 Read now: The SURPASS-EARLY trial

Summary: Macrogol (polyethylene glycol) and docusate sodium are generally considered the safest and most effective stool softeners for patients taking Ozempic, with macrogol often preferred for regular use due to its efficacy and lack of dependency risk

Magnesium: the forgotten electrolytea review on hypomagnesemia

[1] NICE guidance (NG28) recommends GLP-1 receptor agonists like semaglutide for adults with type 2 diabetes when: Triple therapy with metformin and two other oral drugs is ineffective, not tolerated, or contraindicated The person has a BMI of 35 kg/m or higher (adjusted for ethnicity) and specific psychological or medical problems associated with obesity BMI is lower than 35 kg/m but insulin therapy would have significant occupational implications or weight loss would benefit other obesity-related comorbidities Ozempic is available in pre-filled, multi-dose pens delivering 0.25 mg, 0.5 mg, 1 mg, or 2 mg doses

Sheng Y, Wu T, Dai Y, Xu L, Zhong Y, Xue Y, Tian Y (2020a) 6-gingerol alleviates inflammatory injury in DSS-induced ulcerative colitis mice by regulating NF-B signaling