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Age-dependent accumulation of oligomeric SNCA/-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: Role for therapeutic activation of chaperone-mediated autophagy (CMA)
These challenges underscore the urgent need for innovative and effective drugs to overcome these shortcomings and provide more effective and tolerable treatments for UC patients
The evidence is preclinical mouse and cell studies
In research settings vials are stored upright toward the back of the fridge, where the temperature is most stable
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