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In a separate 12-month prospective study of 65 patients with type 2 diabetes mellitus (T2DM) initiating GLP-1 RA therapy (dulaglutide or semaglutide), significant reductions in body weight and BMI were also observed
The severe complication ischemic colitis was reported incidentally, which first led to withdrawal of alosetron in the USA
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Both medications share similar side effect profiles, with GI symptoms being most common and typically improving over time
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