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Semaglutide was originally developed by Novo Nordisk as an antidiabetic agent under the brand name Ozempic (0.52 mg weekly, subcutaneous), approved by the FDA in 2017 for type 2 diabetes management
In addition, he had a keen interest in diabetes, having treated many such patients while working with Yalow
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However, individual variation exists: patients with low baseline eGFR, chronic kidney disease, or conditions predisposing to stone formation warrant closer scrutiny and provider oversight before initiating GLP-1 therapy
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