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Ozempic and Wegovy (semaglutide) In 2020 The FDA approved Ozempic (semaglutide) for the reduction of stroke, heart attack, and other major adverse cardiovascular events (MACE) in adults with type 2 diabetes and heart disease
The SURPASS clinical trial program did not identify increased cardiovascular events with tirzepatide compared to placebo or active comparators, though dedicated cardiovascular outcome trials are still ongoing
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Appetite suppression becomes more noticeable
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