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Laussel C, Lon S
Reduced enzymatic production and secretion might happen for several reasons, such as: Dirty genes (born, such as DAO) Dirty enzymes (became dirty due to environment and lifestyle, such as DAO) SIBO (small intestinal bacterial overgrowth) [33] Liver dysfunction Gallbladder dysfunction Nervous system dysregulation (chronic stress, previous traumas) Inflammation (celiac disease, IBD, IBS, atrophic gastritis, pancreatitis, eosinophilic esophagitis, cystic fibrosis) [20] Lifestyle factors (smoking, alcohol consumption, substance abuse) Aging (reduced stomach acid) Nutrient Absorption Large Intestine (aka the Colon): The colon is crucial for absorbing water
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This 28day guideline comes from the USP Compounding Standards, which sets standards for sterile compounding and states that an opened multidose vial with antimicrobial preservative should be discarded within 28 days unless the manufacturer specifies otherwise
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