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Well, as you do that, but, let me ask it a little differently
Dosage matters: if the dose is too high too fast, side effects like nausea, vomiting, or diarrhea become more likely, reducing adherence
Elevated levels of GLP-1 with GLP-1RA prompt increased insulin secretion and decreased glucagon production
Phase 2 trials are primarily designed to assess dose-response relationships and safety signals rather than to definitively establish efficacy at a population level
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