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Sleep changes, appetite shifts, and social withdrawal often appear days or weeks before severe symptoms
Administration of polymannuronic acid (30 mg/kg, p.o., for 4 weeks) significantly increased the expressions of ZO-1 and occludin in both the colon and SNpc, indicating that the integrity of the intestinal barrier and BBB improved in response to polymannuronic acid intake in 8-week-old MPPT mice [44]
Swapping metagenomics preprocessing pipeline components offers speed and sensitivity increases
10.1016/S0014-5793(97)00591-7 FEBS Lett
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