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4750 The effect of intravenous infusion of GLP-1 on food intake disappeared after vagotomy in humans, which suggested that the vagus afferent pathway is involved in the effect of GLP-1 on appetite

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Muhoberac, B

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Thus, it appears possible to divorce nausea from satiation in mice treated with GLP-1R agonists by discovery of GLP-1R agonists that preferentially access and activate the NTS but not the AP

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