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To explore the therapeutic effect on cell fitness, we selected primary patient-derived fibroblast cell lines with confirmed mitochondrial translation defects 48,49,50
According to epidemiological research, non-motor symptoms frequently occur decades before motor start, indicating early peripheral involvement
Laboratory research record on L-Carnitine [PMID: 20946020] PubMed laboratory record discussing L-Carnitine in a research context
Incomplete FAO leads to the accumulation of even-chain acylcarnitines from C4 to C22 in the mitochondria, with a corresponding decrease in carnitine levels [6]
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