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Determinants of platelet activation in human essential hypertension

212 SAFETY AND EFFICACY OF DAPAGLIFLOZIN IN RECURRENT ASCITES: A PILOT STUDY Virendra Singh 1 , Arka De 2 , Rishav Aggarwal 1 , Shivani Chandel 1 , Akash Gandotra 2 and Naveen Dandia 1 , (1)Postgraduate Institute of Medical Education and Research, (2)Post Graduate Institute of Medical Education and Research Background: The pathophysiology of ascites in cirrhosis entails vasodilatation with the consequential activation of sympathetic nervous system and renin-angiotensin-aldosterone system, leading to retention of sodium and water

It has not undergone Phase I, II, or III human clinical trials and is not recognized as Generally Recognized as Safe (GRAS)

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