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The Journal of Managed Care & Specialty Pharmacy reported less than one-third of patients stayed on GLP-1s for a full year, and only 27% took their medications as intended
In contrast, semaglutide, despite its widespread clinical use for glycemic control and weight loss, showed minimal interaction with neurodegenerative pathways within the DM2-AD comorbidity network, suggesting that its metabolic benefits may not translate into AD risk reduction through core disease-associated mechanisms
doi:10.1002/14651858.cd006423.pub2
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