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Firstly, the genetic variants used should be associated with the exposure
A systematic review and meta-analysis published in the International Journal of Obesity examined multiple randomised controlled trials and found that green tea catechins, particularly when combined with caffeine, produced statistically significant but modest reductions in body weight (approximately 1.3 kg over 12 weeks) and small increases in energy expenditure
That said, like any therapy, there are some potential side effects and precautions to be aware of
It analyzes pathway-level variants (FTO) that relate to the biology involved, offering context for a conversation with your provider rather than a prediction
