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It activates amylin and calcitonin receptors in the hypothalamus
HUBERMAN: And this is very important to understand because unlike a lot of our discussion on this podcast about dopamine or about specific hormones like testosterone or estrogen, when we talk about peptides, especially therapeutic peptides, oftentimes we're talking about a single peptide that does a bunch of different things depending on the cell type, the time of day or night that that peptide is present, and even the different so-called downstream effects of the peptide
Moreover, the negative effects of type I IFNs on antitumor immunity, including the induction of immunosuppressive molecules, the enhancement of Treg function, and the promotion of T-cell exhaustion, should also be recognized [283]
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